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Statistical methods for cis‐Mendelian randomization with two‐sample summary‐level data

Mendelian randomization (MR) is the use of genetic variants to assess the existence of a causal relationship between a risk factor and an outcome of interest. Here, we focus on two‐sample summary‐data MR analyses with many correlated variants from a single gene region, particularly on cis‐MR studies...

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Detalhes bibliográficos
Publicado no:Genet Epidemiol
Main Authors: Gkatzionis, Apostolos, Burgess, Stephen, Newcombe, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2022
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614127/
https://ncbi.nlm.nih.gov/pubmed/36273411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22506
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