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Crescents derive from single podocyte progenitors and a drug enhancing their differentiation attenuates crescentic glomerulonephritis*
Crescentic glomerulonephritis is characterized by vascular necrosis and the formation of parietal epithelial cell (PEC) hyperplasia, but little is known about the molecular mechanisms driving this process. Inducing crescentic glomerulonephritis in several Pax2Cre reporter mouse lines revealed that c...
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| Publicat a: | Sci Transl Med |
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| Autors principals: | , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2022
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7614034/ https://ncbi.nlm.nih.gov/pubmed/35947676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.abg3277 |
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