The effect of LPA Thr3888Pro on lipoprotein(a) and coronary artery disease is modified by the LPA KIV-2 variant 4925G>A

BACKGROUND AND AIMS: High lipoprotein(a) [Lp(a)] concentrations are associated with increased coronary artery disease (CAD) risk. Lp(a) is regulated mainly genetically by the LPA gene but involved genetic variants have not been fully elucidated. Improved understanding of the entanglements of genetic...

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Publicado en:Atherosclerosis
Autores principales: Grüneis, Rebecca, Lamina, Claudia, Di Maio, Silvia, Schönherr, Sebastian, Zoescher, Peter, Forer, Lukas, Streiter, Gertraud, Peters, Annette, Gieger, Christian, Köttgen, Anna, Kronenberg, Florian, Coassin, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2022
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613586/
https://ncbi.nlm.nih.gov/pubmed/35534298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2022.04.023
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