A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction

AIMS: Lp(a) concentrations represent a major cardiovascular risk factor and are almost entirely controlled by one single locus (LPA). However, many genetic factors in LPA governing the enormous variance of Lp(a) levels are still unknown. Since up to 70% of the LPA coding sequence are located in a di...

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Bibliografski detalji
Izdano u:Eur Heart J
Glavni autori: Coassin, Stefan, Erhart, Gertraud, Weissensteiner, Hansi, Eca Guimarães de Araújo, Mariana, Lamina, Claudia, Schönherr, Sebastian, Forer, Lukas, Haun, Margot, Losso, Jamie Lee, Köttgen, Anna, Schmidt, Konrad, Utermann, Gerd, Peters, Annette, Gieger, Christian, Strauch, Konstantin, Finkenstedt, Armin, Bale, Reto, Zoller, Heinz, Paulweber, Bernhard, Eckardt, Kai-Uwe, Hüttenhofer, Alexander, Huber, Lukas A., Kronenberg, Florian
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Fast Track Clinical Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5837733/
https://ncbi.nlm.nih.gov/pubmed/28444229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehx174
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