A comprehensive map of single-base polymorphisms in the hypervariable LPA kringle IV type 2 copy number variation region

Lipoprotein (a) [Lp(a)] concentrations are among the strongest genetic risk factors for cardiovascular disease and present pronounced interethnic and interindividual differences. Approximately 90% of Lp(a) variance is controlled by the LPA gene, which contains a 5.6-kb-large copy number variation [k...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Autores principales: Coassin, Stefan, Schönherr, Sebastian, Weissensteiner, Hansi, Erhart, Gertraud, Forer, Lukas, Losso, Jamie Lee, Lamina, Claudia, Haun, Margot, Utermann, Gerd, Paulweber, Bernhard, Specht, Günther, Kronenberg, Florian
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Patient-Oriented and Epidemiological Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314250/
https://ncbi.nlm.nih.gov/pubmed/30413653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M090381
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