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In vivo engineered B cells secrete high titers of broadly neutralizing anti-HIV antibodies in mice
Transplantation of B cells engineered ex vivo to secrete broadly neutralizing antibodies (bNAbs) has shown efficacy in disease models. However, clinical translation of this approach would require specialized medical centers, technically demanding protocols and MHC compatibility of donor cells and re...
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| Publicado no: | Nat Biotechnol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2022
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613293/ https://ncbi.nlm.nih.gov/pubmed/35681059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-022-01328-9 |
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