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Accurate detection of tumor-specific gene fusions reveals strongly immunogenic personal neo-antigens
Cancer associated gene fusions (GF) are a potential source for highly immunogenic neo-antigens, but the lack of computational tools for accurate, sensitive identification of personal GFs has limited their targeting in personalized cancer immunotherapy. Here, we present EasyFuse, a machine learning c...
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| Veröffentlicht in: | Nat Biotechnol |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2022
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613288/ https://ncbi.nlm.nih.gov/pubmed/35379963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-022-01247-9 |
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