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Identification of neoantigens for individualised cancer immunotherapy
Cancer is characterised by an accumulation of somatic mutations. These can generate cancer-specific neoepitopes that are recognised by autologous T cells in the tumour-bearing host. As neoepitopes are not subject to central immune tolerance and not expressed in healthy tissues, they are attractive t...
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| Izdano u: | Nat Rev Drug Discov |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2022
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7612664/ https://ncbi.nlm.nih.gov/pubmed/35105974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-021-00387-y |
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