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Mutanome Engineered RNA Immunotherapy: Towards Patient-Centered Tumor Vaccination

Advances in nucleic acid sequencing technologies have revolutionized the field of genomics, allowing the efficient targeting of mutated neoantigens for personalized cancer vaccination. Due to their absence during negative selection of T cells and their lack of expression in healthy tissue, tumor mut...

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Bibliografische gegevens
Gepubliceerd in:J Immunol Res
Hoofdauteurs: Vormehr, Mathias, Schrörs, Barbara, Boegel, Sebastian, Löwer, Martin, Türeci, Özlem, Sahin, Ugur
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710911/
https://ncbi.nlm.nih.gov/pubmed/26844233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/595363
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