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Mutanome Engineered RNA Immunotherapy: Towards Patient-Centered Tumor Vaccination

Advances in nucleic acid sequencing technologies have revolutionized the field of genomics, allowing the efficient targeting of mutated neoantigens for personalized cancer vaccination. Due to their absence during negative selection of T cells and their lack of expression in healthy tissue, tumor mut...

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Detalhes bibliográficos
Publicado no:J Immunol Res
Main Authors: Vormehr, Mathias, Schrörs, Barbara, Boegel, Sebastian, Löwer, Martin, Türeci, Özlem, Sahin, Ugur
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710911/
https://ncbi.nlm.nih.gov/pubmed/26844233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/595363
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