Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover

Focal adhesions are multifunctional organelles that couple cell-matrix adhesion to cytoskeletal force transmission and signaling and to steer cell migration and collective cell behavior. Whereas proteomic changes at focal adhesions are well understood, little is known about signaling lipids in focal...

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Publicat a:Dev Cell
Autors principals: Posor, York, Kampyli, Charis, Bilanges, Benoit, Ganguli, Sushila, Koch, Philipp A., Wallroth, Alexander, Morelli, Daniele, Jenkins, Michalina, Alliouachene, Samira, Deltcheva, Elitza, Baum, Buzz, Haucke, Volker, Vanhaesebroeck, Bart
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2022
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613278/
https://ncbi.nlm.nih.gov/pubmed/35809565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2022.06.011
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