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Substitution mutational signatures in whole-genome-sequenced cancers in the UK population
Whole-genome sequencing (WGS) permits comprehensive cancer genome analyses, revealing mutational signatures, imprints of DNA damage and repair processes that have arisen in each patient’s cancer. We performed mutational signature analyses on 12,222 WGS tumor-normal matched pairs, from patients recru...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2022
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613262/ https://ncbi.nlm.nih.gov/pubmed/35949260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abl9283 |
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