4-Octyl-itaconate and dimethyl fumarate inhibit COX2 expression and prostaglandin production in macrophages

Prostaglandins (PGs) are important proinflammatory lipid mediators, the significance of which is highlighted by the widespread and efficacious use of non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of inflammation. 4-Octyl itaconate (4-OI), a derivative of the Krebs cycle-derived met...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Diskin, Ciana, Zotta, Alessia, Corcoran, Sarah E., Tyrrell, Victoria J., Zaslona, Zbigniew, O’Donnell, Valerie B., O’Neill, Luke A.J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613254/
https://ncbi.nlm.nih.gov/pubmed/34635585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2100488
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