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4-Octyl-itaconate and dimethyl fumarate inhibit COX2 expression and prostaglandin production in macrophages
Prostaglandins (PGs) are important proinflammatory lipid mediators, the significance of which is highlighted by the widespread and efficacious use of non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of inflammation. 4-Octyl itaconate (4-OI), a derivative of the Krebs cycle-derived met...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7613254/ https://ncbi.nlm.nih.gov/pubmed/34635585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2100488 |
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