Differential cofactor dependencies define distinct types of human enhancers

All multicellular organisms rely on differential gene transcription regulated by genomic enhancers, which function through the transcription-factor-mediated recruitment of cofactors(1,2). Emerging evidence suggests that not all cofactors are required at all enhancers(3–5), yet if these observations...

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Vydáno v:Nature
Hlavní autoři: Neumayr, Christoph, Haberle, Vanja, Serebreni, Leonid, Karner, Katharina, Hendy, Oliver, Boija, Ann, Henninger, Jonathan E., Li, Charles H., Stejskal, Karel, Lin, Gen, Bergauer, Katharina, Pagani, Michaela, Rath, Martina, Mechtler, Karl, Arnold, Cosmas D., Stark, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2022
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7613064/
https://ncbi.nlm.nih.gov/pubmed/35650434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-022-04779-x
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