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Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation

Gene transcription in animals involves the assembly of RNA polymerase II at core promoters and its cell type-specific activation by enhancers that can be located more distally(1). However, how ubiquitous expression of housekeeping genes is achieved has remained less clear. In particular, it is unkno...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nature
Päätekijät: Zabidi, Muhammad A., Arnold, Cosmas D., Schernhuber, Katharina, Pagani, Michaela, Rath, Martina, Frank, Olga, Stark, Alexander
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795551/
https://ncbi.nlm.nih.gov/pubmed/25517091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13994
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