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Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation
Gene transcription in animals involves the assembly of RNA polymerase II at core promoters and its cell type-specific activation by enhancers that can be located more distally(1). However, how ubiquitous expression of housekeeping genes is achieved has remained less clear. In particular, it is unkno...
Shranjeno v:
| izdano v: | Nature |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6795551/ https://ncbi.nlm.nih.gov/pubmed/25517091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13994 |
| Oznake: |
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