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Genome-wide assessment of sequence-intrinsic enhancer responsiveness at single-base-pair resolution

Gene expression is controlled by enhancers that activate transcription from the core promoters of their target genes. Although a key function of core promoters is to convert enhancer activities into gene transcription, whether and how strongly they activate transcription in response to enhancers has...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Arnold, Cosmas D, Zabidi, Muhammad A, Pagani, Michaela, Rath, Martina, Schernhuber, Katharina, Kazmar, Tomáš, Stark, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870828/
https://ncbi.nlm.nih.gov/pubmed/28024147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3739
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