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Imaging Aβ(1–42) fibril elongation reveals strongly polarised growth and growth incompetent states†

The major hallmark of Alzheimer’s disease is the deposition of plaques of amyloid fibrils formed from amyloid-β (Aβ) peptides. Kinetic studies have contributed significantly towards a mechanistic understanding of amyloid fibril self-assembly, however dynamic features of the aggregation process canno...

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Detalhes bibliográficos
Publicado no:Phys Chem Chem Phys
Main Authors: Young, Laurence J., Kaminski Schierle, Gabriele S., Kaminski, Clemens F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612976/
https://ncbi.nlm.nih.gov/pubmed/29026905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cp03412a
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