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Structural progression of amyloid-β Arctic mutant aggregation in cells revealed by multiparametric imaging
The 42-amino-acid β-amyloid (Aβ42) is a critical causative agent in the pathology of Alzheimer's disease. The hereditary Arctic mutation of Aβ42 (E22G) leads to increased intracellular accumulation of β-amyloid in early-onset Alzheimer's disease. However, it remains largely unknown how the...
Shranjeno v:
| izdano v: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6364760/ https://ncbi.nlm.nih.gov/pubmed/30504224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004511 |
| Oznake: |
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