Spatial-CUT&Tag: Spatially Resolved Chromatin Modification Profiling at Cellular Level

Spatial omics emerged as a new frontier of biological and biomedical research. Here we present spatial-CUT&Tag for spatially resolved genome-wide profiling of histone modifications by combining in situ CUT&Tag chemistry, microfluidic deterministic barcoding, and next generation sequencing. S...

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Pubblicato in:Science
Autori principali: Deng, Yanxiang, Bartosovic, Marek, Kukanja, Petra, Zhang, Di, Liu, Yang, Su, Graham, Enninful, Archibald, Bai, Zhiliang, Castelo-Branco, Gonçalo, Fan, Rong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2022
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612972/
https://ncbi.nlm.nih.gov/pubmed/35143307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abg7216
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