A specific circuit in the midbrain detects stress and induces restorative sleep

In mice, social defeat stress (SDS), an ethological model for psychosocial stress, induces sleep. Such sleep could enable resilience, but how stress promotes sleep is unclear. Activity-dependent tagging revealed a subset of ventral tegmental area GABA-somatostatin (VTA(Vgat-Sst)) cells that sense st...

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Published in:Science
Main Authors: Yu, Xiao, Zhao, Guangchao, Wang, Dan, Wang, Sa, Li, Rui, Li, Ao, Wang, Huan, Nollet, Mathieu, Chun, You Young, Zhao, Tianyuan, Yustos, Raquel, Li, Huiming, Zhao, Jianshuai, Li, Jiannan, Cai, Min, Vyssotski, Alexei L., Li, Yulong, Dong, Hailong, Franks, Nicholas P., Wisden, William
Format: Artigo
Language:Inglês
Published: 2022
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612951/
https://ncbi.nlm.nih.gov/pubmed/35771921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abn0853
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