Single-cell reconstruction of the early maternal–fetal interface in humans

During early human pregnancy the uterine mucosa transforms into the decidua, into which the fetal placenta implants and where placental trophoblast cells intermingle and communicate with maternal cells. Trophoblast–decidual interactions underlie common diseases of pregnancy, including pre-eclampsia...

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Published in:Nature
Main Authors: Vento-Tormo, Roser, Efremova, Mirjana, Botting, Rachel A., Turco, Margherita Y., Vento-Tormo, Miquel, Meyer, Kerstin B., Park, Jong-Eun, Stephenson, Emily, Polański, Krzysztof, Goncalves, Angela, Gardner, Lucy, Holmqvist, Staffan, Henriksson, Johan, Zou, Angela, Sharkey, Andrew M., Millar, Ben, Innes, Barbara, Wood, Laura, Wilbrey-Clark, Anna, Payne, Rebecca P., Ivarsson, Martin A., Lisgo, Steve, Filby, Andrew, Rowitch, David H., Bulmer, Judith N., Wright, Gavin J., Stubbington, Michael J. T., Haniffa, Muzlifah, Moffett, Ashley, Teichmann, Sarah A.
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612850/
https://ncbi.nlm.nih.gov/pubmed/30429548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0698-6
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