Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine

ChRmine, a recently discovered pump-like cation-conducting channelrhodopsin, exhibits puzzling properties (large photocurrents, red-shifted spectrum, and extreme light sensitivity) that have created new opportunities in optogenetics. ChRmine and its homologs function as ion channels but, by primary...

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Vydáno v:Cell
Hlavní autoři: Kishi, Koichiro E., Kim, Yoon Seok, Fukuda, Masahiro, Inoue, Masatoshi, Kusakizako, Tsukasa, Wang, Peter Y., Ramakrishnan, Charu, Byrne, Eamon F.X., Thadhani, Elina, Paggi, Joseph M., Matsui, Toshiki E., Yamashita, Keitaro, Nagata, Takashi, Konno, Masae, Quirin, Sean, Lo, Maisie, Benster, Tyler, Uemura, Tomoko, Liu, Kehong, Shibata, Mikihiro, Nomura, Norimichi, Iwata, So, Nureki, Osamu, Dror, Ron O., Inoue, Keiichi, Deisseroth, Karl, Kato, Hideaki E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2022
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612760/
https://ncbi.nlm.nih.gov/pubmed/35114111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2022.01.007
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