Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine

ChRmine, a recently discovered pump-like cation-conducting channelrhodopsin, exhibits puzzling properties (large photocurrents, red-shifted spectrum, and extreme light sensitivity) that have created new opportunities in optogenetics. ChRmine and its homologs function as ion channels but, by primary...

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Bibliografiske detaljer
Udgivet i:Cell
Main Authors: Kishi, Koichiro E., Kim, Yoon Seok, Fukuda, Masahiro, Inoue, Masatoshi, Kusakizako, Tsukasa, Wang, Peter Y., Ramakrishnan, Charu, Byrne, Eamon F.X., Thadhani, Elina, Paggi, Joseph M., Matsui, Toshiki E., Yamashita, Keitaro, Nagata, Takashi, Konno, Masae, Quirin, Sean, Lo, Maisie, Benster, Tyler, Uemura, Tomoko, Liu, Kehong, Shibata, Mikihiro, Nomura, Norimichi, Iwata, So, Nureki, Osamu, Dror, Ron O., Inoue, Keiichi, Deisseroth, Karl, Kato, Hideaki E.
Format: Artigo
Sprog:Inglês
Udgivet: 2022
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612760/
https://ncbi.nlm.nih.gov/pubmed/35114111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2022.01.007
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