The importance of targeting signalling mechanisms of the SLC39A family of zinc transporters to inhibit endocrine resistant breast cancer

AIM: Zinc is a key secondary messenger that can regulate multiple signalling pathways within cancer cells, thus its levels need to be strictly controlled. The Zrt, Irt-like protein (ZIP, SLC39A) family of zinc transporters increase cytosolic zinc from either extracellular or intracellular stores. Th...

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Detalhes bibliográficos
Publicado no:Explor Target Antitumor Ther
Main Authors: Jones, Samuel, Farr, Georgia, Nimmanon, Thirayost, Ziliotto, Silvia, Gee, Julia M.W., Taylor, Kathryn M.
Formato: Artigo
Idioma:Inglês
Publicado em: Open Exploration 2022
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612740/
https://ncbi.nlm.nih.gov/pubmed/35591900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.37349/etat.2022.00080
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