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The importance of targeting signalling mechanisms of the SLC39A family of zinc transporters to inhibit endocrine resistant breast cancer

Aim: Zinc is a key secondary messenger that can regulate multiple signalling pathways within cancer cells, thus its levels need to be strictly controlled. The Zrt, Irt-like protein (ZIP, SLC39A) family of zinc transporters increase cytosolic zinc from either extracellular or intracellular stores. T...

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Autores principales: Samuel Jones, Georgia Farr, Thirayost Nimmanon, Silvia Ziliotto, Julia M.W. Gee, Kathryn M. Taylor
Formato: Artigo
Lenguaje:Inglês
Publicado: Open Exploration Publishing Inc. 2022-04-01
Colección:Exploration of Targeted Anti-tumor Therapy
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Acceso en línea:https://www.explorationpub.com/Journals/etat/Article/100280
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