The Candida albicans toxin candidalysin mediates distinct epithelial inflammatory responses through p38 and EGFR-ERK pathways

The fungal pathogen Candida albicans secretes the peptide toxin candidalysin, which damages epithelial cells and drives an innate inflammatory response mediated by the epidermal growth factor receptor (EGFR) and mitogen-activated protein kinase (MAPK) pathways and the transcription factor c-Fos. In...

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Vydáno v:Sci Signal
Hlavní autoři: Nikou, Spyridoula-Angeliki, Zhou, Chunsheng, Griffiths, James S., Kotowicz, Natalia K., Coleman, Bianca M., Green, Mary J., Moyes, David L., Gaffen, Sarah L., Naglik, Julian R., Parker, Peter J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2022
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612652/
https://ncbi.nlm.nih.gov/pubmed/35380879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.abj6915
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