Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma

Communication between tumors and the stroma of tumor-draining lymph nodes (TDLN) exists before metastasis arises, altering the structure and function of the TDLN niche. Transcriptional profiling of fibroblastic reticular cells (FRC), the dominant stromal population of lymph nodes, has revealed that...

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Detaylı Bibliyografya
Yayımlandı:Cancer Immunol Res
Asıl Yazarlar: Riedel, Angela, Helal, Moutaz, Pedro, Luisa, Swietlik, Jonathan J., Shorthouse, David, Schmitz, Werner, Haas, Lisa, Young, Timothy, da Costa, Ana S.H., Davidson, Sarah, Bhandare, Pranjali, Wolf, Elmar, Hall, Benjamin A., Frezza, Christian, Oskarsson, Thordur, Shields, Jacqueline D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for Cancer Research 2022
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612582/
https://ncbi.nlm.nih.gov/pubmed/35362044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-21-0778
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