Tumor-Derived Lactic Acid Modulates Activation and Metabolic Status of Draining Lymph Node Stroma

Communication between tumors and the stroma of tumor-draining lymph nodes (TDLN) exists before metastasis arises, altering the structure and function of the TDLN niche. Transcriptional profiling of fibroblastic reticular cells (FRC), the dominant stromal population of lymph nodes, has revealed that...

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Vydáno v:Cancer Immunol Res
Hlavní autoři: Riedel, Angela, Helal, Moutaz, Pedro, Luisa, Swietlik, Jonathan J., Shorthouse, David, Schmitz, Werner, Haas, Lisa, Young, Timothy, da Costa, Ana S.H., Davidson, Sarah, Bhandare, Pranjali, Wolf, Elmar, Hall, Benjamin A., Frezza, Christian, Oskarsson, Thordur, Shields, Jacqueline D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for Cancer Research 2022
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612582/
https://ncbi.nlm.nih.gov/pubmed/35362044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-21-0778
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