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Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits

Neurotransmitters, such as γ-aminobutyric acid, glutamate, acetyl choline, glycine and the monoamines, facilitate the crosstalk within the central nervous system. The designated neurotransmitter transporters (NTTs) both release and take up neurotransmitters to and from the synaptic cleft. NTT dysfun...

詳細記述

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書誌詳細
出版年:Pharmacol Ther
主要な著者: Bhat, Shreyas, El-Kasaby, Ali, Freissmuth, Michael, Sucic, Sonja
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612411/
https://ncbi.nlm.nih.gov/pubmed/33310157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2020.107785
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