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Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits

Neurotransmitters, such as γ-aminobutyric acid, glutamate, acetyl choline, glycine and the monoamines, facilitate the crosstalk within the central nervous system. The designated neurotransmitter transporters (NTTs) both release and take up neurotransmitters to and from the synaptic cleft. NTT dysfun...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Bhat, Shreyas, El-Kasaby, Ali, Freissmuth, Michael, Sucic, Sonja
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612411/
https://ncbi.nlm.nih.gov/pubmed/33310157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2020.107785
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