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Functional and Biochemical Consequences of Disease Variants in Neurotransmitter Transporters: A Special Emphasis on Folding and Trafficking Deficits

Neurotransmitters, such as γ-aminobutyric acid, glutamate, acetyl choline, glycine and the monoamines, facilitate the crosstalk within the central nervous system. The designated neurotransmitter transporters (NTTs) both release and take up neurotransmitters to and from the synaptic cleft. NTT dysfun...

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Bibliografiske detaljer
Udgivet i:Pharmacol Ther
Main Authors: Bhat, Shreyas, El-Kasaby, Ali, Freissmuth, Michael, Sucic, Sonja
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7612411/
https://ncbi.nlm.nih.gov/pubmed/33310157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2020.107785
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