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Reciprocal Transcription Factor Networks Govern Tissue-Resident ILC3 Subset Function and Identity

Innate Lymphoid Cells (ILCs) are guardians of mucosal immunity, yet the transcriptional networks that support their function remain poorly understood. We employed inducible combinatorial deletion of key transcription factors (TFs) required for ILC development (RORγt, RORα and T-bet) to determine the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Immunol
Egile Nagusiak: Fiancette, Rémi, Finlay, Conor, Willis, Claire, Bevington, Sarah L., Soley, Jake, Ng, Sky T.H., Baker, Syed Murtuza, Andrews, Simon, Hepworth, Matthew R., Withers, David R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611981/
https://ncbi.nlm.nih.gov/pubmed/34556884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-021-01024-x
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