Reciprocal Transcription Factor Networks Govern Tissue-Resident ILC3 Subset Function and Identity

Innate Lymphoid Cells (ILCs) are guardians of mucosal immunity, yet the transcriptional networks that support their function remain poorly understood. We employed inducible combinatorial deletion of key transcription factors (TFs) required for ILC development (RORγt, RORα and T-bet) to determine the...

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Publicat a:Nat Immunol
Autors principals: Fiancette, Rémi, Finlay, Conor, Willis, Claire, Bevington, Sarah L., Soley, Jake, Ng, Sky T.H., Baker, Syed Murtuza, Andrews, Simon, Hepworth, Matthew R., Withers, David R.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611981/
https://ncbi.nlm.nih.gov/pubmed/34556884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-021-01024-x
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