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A unified haplotype-based method for accurate and comprehensive variant calling
Almost all haplotype-based variant callers were designed specifically for detecting common germline variation in diploid populations, and give suboptimal results in other scenarios. Here we present Octopus, a variant caller that uses a polymorphic Bayesian genotyping model capable of modeling sequen...
שמור ב:
| הוצא לאור ב: | Nat Biotechnol |
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| Main Authors: | , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2021
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611855/ https://ncbi.nlm.nih.gov/pubmed/33782612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-021-00861-3 |
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