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Induction of immunogenic cell death in cancer cells by a photoactivated platinum(IV) prodrug
The platinum((IV)) prodrug trans,trans,trans-[Pt(N(3))(2)(OH)(2)(py)(2)] (1) is stable and non-toxic in the dark, but potently cytotoxic to cancer cells when irradiated by visible light, including cisplatin-resistant cells. On irradiation with visible light, it generates reactive Pt(II) species whic...
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| Veröffentlicht in: | Inorg Chem Front |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611682/ https://ncbi.nlm.nih.gov/pubmed/34540235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0qi00991a |
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