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Conformation Sensitive Targeting of Lipid Nanoparticles for RNA Therapeutics
The successful in vivo implementation of gene expression modulation strategies relies on effective, non-immunogenic delivery vehicles. Lipid nanoparticles (LNPs) are one of the most advanced, non-viral clinically approved nucleic-acid delivery systems. Yet, LNPs accumulate naturally in liver cells u...
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| 發表在: | Nat Nanotechnol |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611664/ https://ncbi.nlm.nih.gov/pubmed/34140675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41565-021-00928-x |
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