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NKX3.1 localization to mitochondria suppresses prostate cancer initiation
Mitochondria provide the front-line of defense against the tumor-promoting effects of oxidative stress. Here we show that the prostate-specific homeoprotein, NKX3.1, suppresses prostate cancer initiation by protecting mitochondria from oxidative stress. Integrating analyses of genetically-engineered...
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| Publicado no: | Cancer Discov |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611624/ https://ncbi.nlm.nih.gov/pubmed/33893149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-20-1765 |
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