Co-clinical Analysis of a Genetically Engineered Mouse Model and Human Prostate Cancer Reveals Significance of NKX3.1 Expression for Response to 5α-reductase Inhibition

BACKGROUND: Although men on active surveillance for prostate cancer (PCa) may benefit from intervention with 5α-reductase inhibitors (5-ARIs), it has not been resolved whether 5-ARIs are effective for delaying disease progression and, if so, whether specific patients are more likely to benefit. OBJE...

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Pubblicato in:Eur Urol
Autori principali: Dutta, Aditya, Panja, Sukanya, Virk, Renu K., Kim, Jaime Yeji, Zott, Roseann, Cremers, Serge, Golombos, David M., Liu, Deli, Mosquera, Juan Miguel, Mostaghel, Elahe A., Barbieri, Christopher E., Mitrofanova, Antonina, Abate-Shen, Cory
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600823/
https://ncbi.nlm.nih.gov/pubmed/28385453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2017.03.031
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