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Gating-related Structural Dynamics of the MgtE Magnesium Channel in Membrane-Mimetics Utilizing Site-Directed Tryptophan Fluorescence
Magnesium is the most abundant divalent cation present in the cell, and an abnormal Mg(2+) homeostasis is associated with several diseases in humans. However, among ion channels, the mechanisms of intracellular regulation and transport of Mg(2+) are poorly understood. MgtE is a homodimeric Mg(2+)-se...
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| Udgivet i: | J Mol Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7611467/ https://ncbi.nlm.nih.gov/pubmed/33203509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.10.025 |
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