The structure of MgtE in the absence of magnesium provides new insights into channel gating

MgtE is a Mg(2+) channel conserved in organisms ranging from prokaryotes to eukaryotes, including humans, and plays an important role in Mg(2+) homeostasis. The previously determined MgtE structures in the Mg(2+)-bound, closed-state, and structure-based functional analyses of MgtE revealed that the...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Jin, Fei, Sun, Minxuan, Fujii, Takashi, Yamada, Yurika, Wang, Jin, Maturana, Andrés D., Wada, Miki, Su, Shichen, Ma, Jinbiao, Takeda, Hironori, Kusakizako, Tsukasa, Tomita, Atsuhiro, Nakada-Nakura, Yoshiko, Liu, Kehong, Uemura, Tomoko, Nomura, Yayoi, Nomura, Norimichi, Ito, Koichi, Nureki, Osamu, Namba, Keiichi, Iwata, So, Yu, Ye, Hattori, Motoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8104411/
https://ncbi.nlm.nih.gov/pubmed/33905418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001231
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