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Mg(2+)-dependent gating of bacterial MgtE channel underlies Mg(2+) homeostasis

The MgtE family of Mg(2+) transporters is ubiquitously distributed in all phylogenetic domains. Recent crystal structures of the full-length MgtE and of its cytosolic domain in the presence and absence of Mg(2+) suggested a Mg(2+)-homeostasis mechanism, in which the MgtE cytosolic domain acts as a ‘...

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Detalhes bibliográficos
Main Authors: Hattori, Motoyuki, Iwase, Norihiko, Furuya, Noritaka, Tanaka, Yoshiki, Tsukazaki, Tomoya, Ishitani, Ryuichiro, Maguire, Michael E, Ito, Koichi, Maturana, Andres, Nureki, Osamu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782099/
https://ncbi.nlm.nih.gov/pubmed/19798051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.288
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