Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers

Actomyosin machinery endows cells with contractility at a single cell level. However, within a monolayer, cells can be contractile or extensile based on the direction of pushing or pulling forces exerted by their neighbours or on the substrate. It has been shown that a monolayer of fibroblasts behav...

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Veröffentlicht in:Nat Mater
Hauptverfasser: Balasubramaniam, Lakshmi, Doostmohammadi, Amin, Saw, Thuan Beng, Sankara Narayana, Gautham Hari Narayana, Mueller, Romain, Dang, Tien, Thomas, Minnah, Gupta, Shafali, Sonam, Surabhi, Yap, Alpha S., Toyama, Yusuke, Mege, René-Marc, Yeomans, Julia, Ladoux, Benoît
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611436/
https://ncbi.nlm.nih.gov/pubmed/33603188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41563-021-00919-2
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