Topological defects in epithelia govern cell death and extrusion

Epithelia remove excess cells through extrusion, and prevent accumulation of unnecessary or pathological cells. The extrusion process can be triggered by apoptotic signaling1, oncogenic transformation2,3, and overcrowding of cells4–6. Despite the important links of cell extrusion to developmental7,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nature
Prif Awduron: Saw, Thuan Beng, Doostmohammadi, Amin, Nier, Vincent, Kocgozlu, Leyla, Thampi, Sumesh, Toyama, Yusuke, Marcq, Philippe, Lim, Chwee Teck, Yeomans, Julia M, Ladoux, Benoit
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5439518/
https://ncbi.nlm.nih.gov/pubmed/28406198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21718
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