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Topological defects in epithelia govern cell death and extrusion
Epithelia remove excess cells through extrusion, and prevent accumulation of unnecessary or pathological cells. The extrusion process can be triggered by apoptotic signaling1, oncogenic transformation2,3, and overcrowding of cells4–6. Despite the important links of cell extrusion to developmental7,...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5439518/ https://ncbi.nlm.nih.gov/pubmed/28406198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature21718 |
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