Generation, functional analysis and applications of isogenic three-dimensional self-aggregating cardiac microtissues from human pluripotent stem cells

Tissue-like structures from human pluripotent stem cells containing multiple cell types are transforming our ability to model and understand human development and disease. Here we describe a protocol to generate cardiomyocytes (CMs), cardiac fibroblasts and cardiac endothelial cells, the three princ...

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Bibliographic Details
Published in:Nat Protoc
Main Authors: Campostrini, Giulia, Meraviglia, Viviana, Giacomelli, Elisa, van Helden, Ruben W.J., Yiangou, Loukia, Davis, Richard P., Bellin, Milena, Orlova, Valeria V., Mummery, Christine L.
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611409/
https://ncbi.nlm.nih.gov/pubmed/33772245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-021-00497-2
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