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Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells

Cardiomyocytes and endothelial cells in the heart are in close proximity and in constant dialogue. Endothelium regulates the size of the heart, supplies oxygen to the myocardium and secretes factors that support cardiomyocyte function. Robust and predictive cardiac disease models that faithfully rec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Giacomelli, Elisa, Bellin, Milena, Sala, Luca, van Meer, Berend J., Tertoolen, Leon G. J., Orlova, Valeria V., Mummery, Christine L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358113/
https://ncbi.nlm.nih.gov/pubmed/28279973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143438
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