Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells

Cardiomyocytes and endothelial cells in the heart are in close proximity and in constant dialogue. Endothelium regulates the size of the heart, supplies oxygen to the myocardium and secretes factors that support cardiomyocyte function. Robust and predictive cardiac disease models that faithfully rec...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Giacomelli, Elisa, Bellin, Milena, Sala, Luca, van Meer, Berend J., Tertoolen, Leon G. J., Orlova, Valeria V., Mummery, Christine L.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Human Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358113/
https://ncbi.nlm.nih.gov/pubmed/28279973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.143438
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