An interdependent network of functional enhancers regulates transcription and EZH2 loading at the INK4a/ARF locus

The INK4a/ARF locus encodes important cell-cycle regulators p14(ARF), p15(INK4b), and p16(INK4a). The neighboring gene desert to this locus is the most reproducible GWAS hotspot that harbors one of the densest enhancer clusters in the genome. However, how multiple enhancers that overlap with GWAS va...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Farooq, Umer, Saravanan, Bharath, Islam, Zubairul, Walavalkar, Kaivalya, Singh, Anurag Kumar, Jayani, Ranveer Singh, Meel, Sweety, Swaminathan, Sudha, Notani, Dimple
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611173/
https://ncbi.nlm.nih.gov/pubmed/33761351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108898
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados