Constructing ion channels from water-soluble α-helical barrels

The design of peptides that assemble in membranes to form functional ion channels is challenging. Specifically, hydrophobic interactions must be designed between the peptides and at the peptide–lipid interfaces simultaneously. Here, we take a multi-step approach towards this problem. First, we use r...

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Detaylı Bibliyografya
Yayımlandı:Nat Chem
Asıl Yazarlar: Scott, Alistair J., Niitsu, Ai, Kratochvil, Huong T., Lang, Eric J. M., Sengel, Jason T., Dawson, William M., Mahendran, Kozhinjampara R., Mravic, Marco, Thomson, Andrew R., Brady, R. Leo, Liu, Lijun, Mulholland, Adrian J., Bayley, Hagan, DeGrado, William F., Wallace, Mark I., Woolfson, Derek N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611114/
https://ncbi.nlm.nih.gov/pubmed/33972753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-021-00688-0
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