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Membrane-spanning α-helical barrels as tractable protein-design targets
The rational (de novo) design of membrane-spanning proteins lags behind that for water-soluble globular proteins. This is due to gaps in our knowledge of membrane-protein structure, and experimental difficulties in studying such proteins compared to water-soluble counterparts. One limiting factor is...
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| Pubblicato in: | Philos Trans R Soc Lond B Biol Sci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5483516/ https://ncbi.nlm.nih.gov/pubmed/28630153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2016.0213 |
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