Mutations in LC3B2 and ATG4A underlie recurrent HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans

Recurrent herpesvirus infections can lead to numerous forms of diseases ranging from cold sore and genital herpes to encephalitis. Currently, there is an incomplete understanding of the genetic and immunological factors conferring susceptibility to recurrent HSV2 infections in the central nervous sy...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Immunol
Main Authors: Hait, Alon Schneider, Olagnier, David, Sancho-Shimizu, Vanessa, Skipper, Kristian Alsbjerg, Helleberg, Marie, Larsen, Simon Muller, Bodda, Chiranjeevi, Moldovan, Liviu Ionut, Ren, Fanghui, Brinck-Andersen, Nanna-Sophie, Thomsen, Michelle M., Freytag, Mette Ratzer, Darmalinggam, Sathya, Parkes, Isobel, Kadekar, Darshana D., Rahbek, Stine Hess, van der Horst, Demi, Kristensen, Lasse Sommer, Eriksson, Kristina, Kjems, Jørgen, Mostowy, Serge, Christiansen, Mette, Mikkelsen, Jacob Giehm, Brandt, Christian Thomas, Paludan, Søren R., Mogensen, Trine H.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2020
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611067/
https://ncbi.nlm.nih.gov/pubmed/33310865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abc2691
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